irak inhibitor 4 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T11672	IRAK inhibitor 4		Others
	IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 inhibitor.		Others
T2457	IRAK-1-4 Inhibitor I	IRAK-1/4 Inhibitor I,IRAK-1/4 Inhibitor	IRAK
	IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.		IRAK
T9631	IRAK-4 protein kinase inhibitor 2		IRAK
	IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM).		IRAK
T11671	IRAK inhibitor 4 trans		SGLT
	IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the activity of IRAK4. The (trans) form of IRAK inhibitor 4 refers...		SGLT
T11673	IRAK4-IN-4		IRAK , cGAS
	IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhibitor, has an IC50 of 2.8 nM.		IRAK , cGAS
T4140	IRAK4-IN-1		IRAK
	IRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM.		IRAK
T4299	AS-2444697		IRAK
	AS-2444697 is an inhibitor of IRAK-4 (C50 = 21 nM). AS-2444697 exhibits renoprotective effects through anti-inflammatory action. AS-2444697 potently inhibits human and rat IRAK-4 activity.		IRAK
T5354	IRAK4-IN-7	CA-4948	IRAK
	IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.		IRAK
T14367	AZ1495		IRAK , CDK , Haspin Kinase
	AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Which Shows activity in treatment of mutant MYD88L265P diffu...		IRAK , CDK , Haspin Kinase
T7368	IRAK inhibitor 2	IRAK-IN-2	IRAK
	IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.		IRAK
T5110	IRAK inhibitor 6		IRAK
	IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).		IRAK
T60012	HS-243		IRAK , MAPK , CDK
	HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.		IRAK , MAPK , CDK
T5094	IRAK inhibitor 1		IRAK , JNK
	IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 μM) and JNK-2 (IC50>10 μM).		IRAK , JNK
T62473	Edecesertib
	Edecesertib (GS-5718) is a selective, orally active IRAK-4 inhibitor that exhibits anti-inflammatory activity. edecessertib can be used to study rheumatoid arthritis (RA) and lupus erythematosus (LE).
T4700	1,3,5-Trihydroxy-4-prenylxanthone
	1,3,5-Trihydroxy-4-prenylxanthone is a relatively potent inhibitor of phosphodiesterase type 5 (PDE5), with an IC50 value of 3.0 μM; it shows in vitro inhibitory activity against acetylcholinesterase (AChE) and butyrylch...
T11674	IRAK4-IN-6		Others
	IRAK4-IN-6 is a selective and orally efficacious inhibitor of IRAK4, demonstrating an IC50 value of 4 nM. This compound specifically targets MyD88 L265P mutant diffuse large B-cell lymphoma [1].		Others